Health care is changing radically and permanently at an unprecedented pace. Consumerism, culture, fiscal realities and technology are converging to disrupt and reshape health care and create new opportunity for those prepared for change. From where we are today, we can envision a future in which your phone becomes an instrument for care, we engage in molecular diagnostics and use Big Data in predictive medicine. Many challenges lie ahead as the health care revolution unfolds. Yet our region can reach a new, higher state of health by doing the same things each of us must do for our own healthy futures: create the right partnerships and make the right choices.